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Table 2 PPPPARγ methylation by sex

From: CpG Methylation across the adipogenic PPARγ gene and its relationship with birthweight and child BMI at 9 years

PPARγ Site CpG Illumina ID Classificationa Methylation at birth (%) Methylation at 9 years (%)
Male (N = 188) Female (N = 185) P valueb Male (N = 113) Female (N = 132) P valueb
1 cg01412654 North Shore 65.8 67.8 0.002 71.5 73.1 0.018
2 cg25929976 North Shore 55.6 58.1 <0.001 62.5 65.4 <0.001
3 cg18063278 North Shore 59.1 62.1 <0.001 68.3 71.1 <0.001
4 cg26364899 Island 6.3 6.3 0.931 6.0 6.2 0.156
5 cg27095527 Island 4.3 4.5 0.289 4.0 4.6 0.380
6 cg06573644 Island 6.2 6.4 0.434 5.8 5.8 0.887
7 cg21946299 Island 9.0 8.9 0.445 9.1 9.0 0.724
8 cg23514324 Island 8.0 8.0 0.943 7.4 7.3 0.626
9 cg04748988 Island 2.3 2.3 0.636 2.0 2.0 0.570
10 cg15722404 Island 2.8 2.7 0.430 2.8 2.7 0.119
11 cg13518792 Island 1.0 1.0 0.297 1.0 1.0 0.564
12 cg09405169 Island 1.9 1.8 0.550 2.1 2.1 0.707
13 cg04632671 Island 1.0 1.1 0.115 1.4 1.2 0.054
14 cg07556134 Island 1.3 1.3 0.797 1.5 1.5 0.457
15 cg18887186 Island 9.8 9.9 0.372 12.5 12.5 0.709
16 cg21859053 South Shore 9.4 9.5 0.459 12.3 12.4 0.657
17 cg04908300 South Shore 15.4 15.9 0.107 24.8 25.7 0.030
18 cgl6827534 South Shelf 87.8 88.6 0.021 89.7 89.4 0.506
19 cg16197186 5′ UTR 91.1 91.3 0.398 92.0 91.9 0.996
20 cg18537222 Gene Body 51.5 52.1 0.612 57.1 58.4 0.345
21 cg07895576 Gene Body 90.1 90.3 0.244 90.7 90.6 0.707
22 cg07676920 Gene Body 85.1 85.0 0.930 85.9 85.4 0.513
23 cg10499651 Gene Body 79.0 78.8 0.632 77.1 78.2 0.084
  1. PPARγ peroxisome proliferator-activated receptor gamma
  2. UTR untranslated region
  3. aBased on Illumina 450 K annotation
  4. bStudent’s t-Test