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Table 2 Clinical profile of the cohort

From: Screening of WT1 mutations in exon 8 and 9 in children with steroid resistant nephrotic syndrome from a single centre and establishment of a rapid screening assay using high-resolution melting analysis in a clinical setting

Characteristic  
Patients (n) 100 (50females/50 males)
Ethnic background (Southern region/Northern region/Eastern region; %) 90/9/1
Consanguinity (%) 12
Onset of NS (congenital/infantile/childhood primary SRNS/Unknown; %) 4/4/80/12
Age at diagnosisa (years; Median, IQR) 2.5 (1.2–6.2)
Edema 74%
Proteinuria (yes/unavailable; %) 81/19
Hematuria (Yes/No/unavailable; %) 13/52/35
Hypertension (yes/no/unavailable) 35/45/20
Serum albumin (g/l; Median, Range) 1.7 (1.2–2.3)
Histopathology subtype (%)  
 Minimal change disease 37
 Focal segmental glomerulosclerosis 21
 Mesangial hypercellularity 12
 Others 9
 Not performed 21
Renal outcome (%)  
 Remission 4
 Persistent relapse 62
 Chronic Kidney disease Stage II-IV 22
 End-stage renal disease 12
  1. aincomplete data on 11/100 patients