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Table 1 Clinical data in seven individuals with bi-allelic WNT10A mutations

From: Abnormal primary and permanent dentitions with ectodermal symptoms predict WNT10A deficiency

Patients Ia Ib II III IV V VI Total
Age at radiographic examination 8.5 7.5 8.0 6.0 16.5 6.5 7.0  
Tooth agenesis in primary dentition 3 0 2 2 0 0 0 7
Tooth agenesis in permanent dentition 28 23 26 16 15 19 22 149
Tapered maxillary central incisors - 2 2 2 1 0 2 9
Molars available for analysis of taurodontisma 75 75 75 - 36 75 75  
85 85 85 85 46 85 85 13
Molars with taurodontisma 1 2 2 1 2 1 2 11
Hyperhidrosis of palms and soles + + - + - + + 5
Coarse hair structure and/or light/scarce/brittle hair + + + + + + + 7
Nail abnormalities - - - - + - + 2
Dry skin + + + + - + + 6
No. of affected ectodermal appendages 3 3 2 3 2 3 4 mean 2.9
  1. aAll were primary molars except for individual IV who had resorbed primary second molars and erupted permanent first molars