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Table 4 Distribution of TGF-β1 polymorphisms genotypes according to age and sex in NPC cases and controls

From: No association between TGF-β1 polymorphisms and risk of nasopharyngeal carcinoma in a large North African case-control study

 

≤30

>30

Genotype

Cases n (%)

Controls n (%)

OR (CI 95 %)a

P-value

Cases n (%)

Controls n (%)

OR (CI 95 %)a

P-value

TGF-β1 −509

 CC

26 (30.23)

30 (38.96)

1.00

-

101 (42.44)

90 (36.44)

1.00

-

 CT

42 (48.84)

31 (40.26)

1.56 (0.77–3.15)

0.211

111 (46.64)

117 (47.37)

0.85 (0.58–1.24)

0.392

 TT

18 (20.93)

16 (20.78)

1.30 (0.55–3.05)

0.549

26 (10.92)

40 (16.19)

0.58 (0.32–1.02)

0.060

TGF-β1 869

 TT

32 (34.04)

23 (29.49)

1.00

-

100 (37.45)

96 (37.35)

1.00

-

 CT

44 (46.81)

42 (53.85)

0.75 (0.38–1.49)

0.415

121 (45.32)

107 (41.63)

1.09 (0.74–1.59)

0.674

 CC

18 (19.15)

13 (16.67)

0.99 (0.41–2.43)

0.992

46 (17.23)

54 (21.01)

0.82 (0.50–1.32)

0.414

 

Men

Women

Genotype

Cases n (%)

Controls n (%)

OR (CI 95 %)a

P-value

Cases n (%)

Controls n (%)

OR (CI 95 %)a

P-value

TGF-β1 −509

 CC

88 (40. 00)

82 (37.27)

1.00

-

39 (37.50)

38 (36.54)

1.00

-

 CT

100 (45.45)

95 (43.18)

0.98 (0.65–1.48)

0.927

53 (50.96)

53 (50.96)

0.97 (0.54–1.75)

0.931

 TT

32 (14.55)

43 (19.55)

0.69 (0.40–1.20)

0.190

12 (11.54)

13 (12.50)

0.90 (0.36–2.22)

0.818

TGF-β1 869

 TT

90 (36.00)

80 (36.20)

1.00

-

42 (37.84)

39 (34.21)

1.00

-

 CT

105 (42.00)

94 (42.53)

0.99 (0.66–1.50)

0.973

60 (54.05)

55 (48.25)

1.01 (0.57–1.80)

0.965

 CC

55 (22.00)

47 (21.27)

1.04 (0.63–1.70)

0.875

9 (8.11)

20 (17.54)

0.42 (0.17–1.03)

0.057

  1. n number of subjects
  2. aUnadjusted Odds ratios and confidence interval for case-control comparison