Fig. 1From: CCM3/SERPINI1 bidirectional promoter variants in patients with cerebral cavernous malformations: a molecular and functional studyTranscription activity analysis of CCM3/SERPINI1 haplotypes of the c.-639 T > C and c.-591 T > C polymorphisms. The transcription activity was measured using the Dual-Luciferase Reporter Assay System in U373 MG (human, Caucasian, glioblastoma-astrocytoma) cells. Luciferase activities are representative of at least three independent experiments, with each construct tested in triplicate per experiment. *p < 0.01; **p > 0.05Back to article page