Fig. 1

Panel a shows the sequence chromatogram of G534E variant in the proband and the reference sequence. Panel b shows the pedigree with the HABP2 genotype for the G534E variant A/G (wild type is G/G). Squares denote male family members, circles female members, shaded symbols affected members and slashes deceased members. *Head and neck irradiation age 16, PTC (T2N1M0) and multiple Hürthle cell adenomas at age 46. ^Multifocal PTC at age 55