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Table 1 List of 18 selected genes studied in patients with nonsyndromic orofacial clefts and normal controls

From: Nonsynonymous variants in MYH9 and ABCA4 are the most frequent risk loci associated with nonsyndromic orofacial cleft in Taiwanese population

Gene

Gene size

(bp)

Map location

Protein

ABCA4

128,313

1p21-p22.1

ATP-binding cassette, sub-family A, member 4

BMP4

9026

6p12

Bone morphogenetic protein 4

CRISPLD2

100,788

16q24.1

Cysteine-rich secretory protein LCCL domain containing 2

GSTT1

8548

22q11.23

Glutathione S-transferase theta 1

FGF8

10,240

10q24.32

Fibroblast growth factor 8

FGFR2

120,129

10q26.13

Fibroblast growth factor receptor 2

FOXE1

3462

9q22

Forkhead box E1

IRF6

20,553

1q32.2

Interferon regulatory factor 6

MAFB

3393

20q12

V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B

MSX1

4272

4p16.2

Msh homeobox 1

MTHFR

21,198

1p36.22

Methylenetetrahydrofolate reductase

MYH9

106,741

22q12.3

Myosin, heavy chain 9

PDGFC

210,941

4q32

Platelet derived growth factor C

PVRL1

105,675

11q23.

Poliovirus receptor-related 1

SUMO1

32,429

17p13.1

Small ubiquitin-like modifier 1

TGFA

106,914

6p21.3

Transforming growth factor, alpha

TGFB3

24,893

14q24.3

Transforming growth factor, beta 3

VAX1

9781

10q25.3

Ventral anterior homeobox 1