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Table 3 Observed distribution of genotypes at the TAS2R38 locus and CRS comorbidities (asthma, allergy, ASA sensitivity) or number of endoscopic surgical procedures in CRS patients, used for association analysis

From: TAS2R38 taste receptor gene and chronic rhinosinusitis: new data from an Italian population

  Asthma Allergy ASA sensitivity N. surgeries Tot.
  Present Absent Present Absent Present Absent 1 >1
PAV/PAV 6 2 3 5 2 6 4 4 8
PAV/- 18 14 19 13 9 23 10 22 32
−/− 6 7 7 6 1 12 5 8 13
Tot. 30 23 29 24 12 41 19 34 53
  1. The following Π values were used to calculate the expected frequencies of each comorbidity (see Table 2): Π(Absence of asthma) = 23/53 = 0.434; Π(Absence of allergy) = 24/53 = 0.453; Π(Absence of ASA sensitivity) = 41/53 = 0.774; Π(1 surgery) = 19/53 = 0.358
  2. Association between genotypes at the TAS2R38 locus and CRS aggravating factors was then tested by χ 2