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Table 1 Demographics and clinical data of the examined population

From: TAS2R38 taste receptor gene and chronic rhinosinusitis: new data from an Italian population

  CTL CRS
Gender, n (male; female) 39 (20; 19) 53 (27; 26)
Age, years (mean ± SD) 46.6 ± 11.9 52.8 ± 14.7
Ethnic group, n (%)   
 • Caucasian 38 (97.4) 52 (98.1)
 • North African 1 (2.6) 1 (1.9)
CRS phenotype   
 • CRSwNP, n (%) - 36 (67.9)
 • CRSsNP, n (%) - 17 (32.1)
Age at first sinus surgery, years (mean ± SD) - 42.9 ± 15.6
Endoscopic sinus surgeries under general anesthesia (mean ± SD) - 2.4 ± 1.7
History of asthma, n (%) - 30 (56.6)
History of allergy, n (%) - 29 (54.7)
History of ASA sensitivity, n (%) - 12 (22.6)
Smoking (current smoker/ex-smoker/non smoker), n (%) 10 (25.6)/6 (15.4)/23 (59) 1 (1.9)/23 (43.4)/29 (54.7)
Family history of CRS/asthma/allergy, n (%) 14 (35.9) 23 (43.4)
TAS2R38 genotype   
 • PAV/PAV, n (%) 7 (17.9) 8 (15.1)
 • PAV/AVI, n (%) 17 (43.6) 29 (54.7)
 • AVI/AVI, n (%) 12 (30.8) 10 (18.9)
 • PAV/AAV, n (%) 1 (2.6) 3 (5.7)
 • AVI/AAV, n (%) 2 (5.1) 2 (3.8)
 • AAV/AAV, n (%) - 1 (1.9)
  1. SD: standard deviation; CRSwNP: chronic rhinosinusitis with nasal polyps; CRSsNP: chronic rhinosinusitis without nasal polyps; ASA: acetyl-salicylic acid