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Table 4 Regression analysis comparing CC carriers of MONET to CAO in women with overweight or obesity

From: Acyl-CoA synthetase long-chain 5 genotype is associated with body composition changes in response to lifestyle interventions in postmenopausal women with overweight and obesity: a genetic association study on cohorts Montréal-Ottawa New Emerging Team, and Complications Associated with Obesity

Multiple regression model

Dependent variable

Number of subjects (n)

Parameter estimate

Standard error

Variable p-value

R2

R2 (adjusted)

Model p-value

1

∆ BMI

123

0.15

1.55

0.923

0.130

0.069

0.038

2

∆ Lean Mass

124

−2.46

1.51

0.105

0.212

0.150

0.001

3

∆ Fat Mass

121

4.73

3.04

0.123

0.233

0.170

<0.001

4

∆ % Lean Mass

126

−2.98

1.72

0.085

0.268

0.212

<0.001

5

∆ % Fat Mass

121

3.98

2.04

0.053

0.315

0.252

<0.001

6

∆ Visceral Fat

124

2.40

5.41

0.658

0.155

0.096

0.011

7

∆ Muscle attenuation

128

0.10

1.02

0.921

0.134

0.091

0.007

  1. * Multiple linear regression analysis was conducted. Independent variables included three dummy variables (CAO CC Carriers, CAO CT/TT carriers and MONET CT/TT carriers) with the exception of MONET CC carriers while adjusting for covariables determined by best subset multiple linear regression, independent for each model (Table 1). The following results illustrate parameter estimates, standard error, p-values corresponding to CAO CC carriers independent variable