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Fig. 1 | BMC Medical Genetics

Fig. 1

From: Genotyping an immunodeficiency causing c.1624–11G>A ZAP70 mutation in Canadian Mennonites

Fig. 1

Ancestral pedigree depicting the relationship between three affected individuals. The common ancestor for three individuals homozygous (shaded symbols; designated with arrows) for the c.1624–11G>A mutation in ZAP70 is an individual who was born in 1816. Individuals heterozygous for c.1624–11G>A are depicted as half-shaded circles and squares, and consanguineous marriages are depicted by double solid lines. Open circles in the bottom generation represent individuals who do not carry the ZAP70 mutation. Not all individuals depicted were tested for the ZAP70 mutation

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