Table 2 Genotype and allele frequencies of SIRT1 polymorphisms in the long-lived individuals and controls

rs12778366

T/T

427 (69.3 %)

578 (68.3 %)

1

0.64

C/T

169 (27.4 %)

246 (29.1 %)

0.93 (0.74–1.17)

C/C

20 (3.2 %)

22 (2.6 %)

1.23 (0.66–2.28)

T

1023 (83.0 %)

1402 (82.9 %)

1

0.90

C

209 (17.0 %)

290 (17.1 %)

0.99 (0.81–1.20)

rs3758391

T/T

441 (71.6 %)

620 (73.5 %)

1

0.72

C/T

161 (26.1 %)

207 (24.5 %)

1.09 (0.86–1.39)

C/C

14 (2.3 %)

17 (2 %)

1.16 (0.56–2.37)

T

1043 (84.7 %)

1447 (85.7 %)

1

0.42

C

189 (15.3 %)

241 (14.3 %)

1.09 (0.88–1.34)

rs3740051

A/A

310 (50.5 %)

436 (51.6 %)

1

0.90

G/A

258 (42 %)

345 (40.8 %)

1.05 (0.85–1.31)

G/G

46 (7.5 %)

64 (7.6 %)

1.01 (0.67–1.52)

A

878 (71.5 %)

1217 (72.0 %)

1

0.76

G

350 (28.5 %)

473 (28.0 %)

1.03 (0.87–1.21)

rs33957861

C/C

425 (69.1 %)

578 (68.3 %)

1

0.91

C/T

170 (27.6 %)

242 (28.6 %)

0.96 (0.76–1.21)

T/T

20 (3.2 %)

26 (3.1 %)

1.05 (0.58–1.90)

C

1020 (82.9 %)

1398 (82.6 %)

1

0.83

T

210 (17.1 %)

294 (17.4 %)

0.98 (0.81–1.19)

rs7896005

A/A

440 (71.5 %)

623 (73.6 %)

1

0.64

G/A

161 (26.2 %)

207 (24.5 %)

1.10 (0.87–1.40)

G/G

14 (2.3 %)

16 (1.9 %)

1.24 (0.60–2.56

A

1041 (84.6 %)

1453 (85.9 %)

0.35

G

189 (15.4 %)

239 (14.1 %)

1.10 (0.90–1.36)

rs12413112

G/G

426 (69.2 %)

576 (68.1 %)

1

0.87

G/A

170 (27.6 %)

244 (28.8 %)

0.94 (0.75–1.19)

A/A

20 (3.2 %)

26 (3.1 %)

1.04 (0.57–1.89)

G

1022 (83.0 %)

1396 (82.5 %)

1

0.75

A

210 (17.0 %)

296 (17.5 %)

0.97 (0.80–1.18)

rs11599176

A/A

423 (68.8 %)

576 (68.1 %)

1

0.92

G/A

172 (28 %)

244 (28.8 %)

0.96 (0.76–1.21)

G/G

20 (3.2 %)

26 (3.1 %)

1.05 (0.58–1.90)

A

1018 (82.8 %)

1396 (82.5 %)

1

0.86

G

212 (17.2 %)

296 (17.5 %)

0.98 (0.81–1.19)

rs4746720

T/T

241 (39.1 %)

314 (37.1 %)

1

0.73

C/T

271 (44 %)

382 (45.1 %)

0.92 (0.74–1.16)

C/C

104 (16.9 %)

150 (17.7 %)

0.90 (0.67–1.22)

T

753 (61.1 %)

1010 (59.7 %)

1

0.45

C

479 (38.9 %)

682 (40.3 %)

0.95 (0.82–1.09)