Skip to main content
Fig. 1 | BMC Medical Genetics

Fig. 1

From: Variants of PLCXD3 are not associated with variant or sporadic Creutzfeldt-Jakob disease in a large international study

Fig. 1

a There is no association signal at the PLCXD3 locus in 2500 sCJD cases compared to 10,548 controls. (b) There is only a modest association signal at the PLCXD3 locus in 129 vCJD cases compared to 5020 UK controls.−Log10(P) values for genotyped and imputed SNPs are plotted against their positions. PLCXD3 SNPs found to be significant in the GWAS by Bishop et al. are indicated in green and PLCXD3 SNPs sequenced by Bishop et al. are in red. Schematic of PLCXD3 gene locus with exons represented in orange and intronic regions by the black line

Back to article page