Table 7 Clinical phenotype of families with founder mutations
| Â | Proband | Family | ||||
|---|---|---|---|---|---|---|
| Â | Sexa | BCbage | OCbage | F-BCc | OCc | M-BCc |
BRCA1c.676delT | Â | Â | Â | Â | Â | Â |
BR128 | F | 41, 51 | - | 3 (2) | 0 | 0 |
BR328 | F | 23 | – | 3 (1) | 1 | 0 |
BR384 | F | 50, 56 | – | 3 (1) | 1 | 0 |
BR392 | F | 30 | – | 4 (1) | 0 | 0 |
BR573 | F | – | 52 | 1 | 3 (2) | 0 |
BR613 | F | – | 53 | 4 (1) | 5 (2) | 0 |
BR704 | F | 29, 31, 31 | – | 1 (1) | 1 | 0 |
BR977 | F | 58 | – | 4 (1) | 0 | 0 |
BR1091 | F | 23, 29 | – | 2 (1) | 0 | 0 |
BR1450 | F | 42 | – | 2(1) | 2 | 0 |
BRCA2 c.7806–2A > G |  |  |  |  |  |  |
BR6 | F | 60 | – | 5 (1) | 0 | 1(1) |
BR60 | F | 45 | – | 8 (3) | 2 (2) | 0 |
BR85 | F | 41 | – | 3 (1) | 0 | 0 |
BR195 | M | 50 | – | 5 | 0 | 3 (1) |
BR243 | M | 70 | – | 4 | 0 | 1 (1) |
BR312 | F | 47 | – | 2 (1) | 0 | 1 |
BR434 | F | 36 | – | 4 (3) | 3 | 0 |
BR594 | F | 36 | – | 1 (1) | 1 | 0 |
BR608 | M | 67 | – | 3 (2) | 0 | 1 (1) |
BR953 | F | 39 | – | 4 (3) | 0 | 1 |
BR1009 | F | 36 | – | 3 (1) | 0 | 0 |
BR1013d | F | – | – | 3 | 0 | 0 |
CFS864 | F | – | 59 | 1 | 1 (1) | 0 |
BR1214 | F | 38 | – | 7 | 0 | 0 |
BR1341 | F | 76 | – | 2 | 0 | 0 |
BR1267 | F | 45 | – | 1bil | 0 | 0 |
BR1548 | F | 48 | – | 5 | 0 | 0 |
BR1481 | F | 48, 69 | 61 | 1 | 0 | 2 |