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Table 4 Association of 32 GWA studies-derived SNP alleles with obesity in Chinese children

From: Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study

SNP Nearest gene Chr. Allele Obesity VS Normal-weight
Effect other OR 95 % CI Two-sided
P-value
Speliotes et al. 2010 (in children and adults of European ancestry) [4]
rs1558902 FTO 16 A T 1.31 1.01-1.69 0.039
rs2867125 TMEM18 2 C T 1.06 0.79-1.42 0.703
rs571312 MC4R 18 A C 1.16 0.94-1.42 0.166
rs10938397 GNPDA2 4 G A 1.19 0.98-1.43 0.077
rs10767664 BDNF 11 A T 1.10 0.93-1.30 0.273
rs2815752 NEGR1 1 A G 1.07 0.79-1.46 0.645
rs7359397 SH2B1 16 T C 1.06 0.85-1.34 0.597
rs9816226 ETV5 3 T A 0.90 0.56-1.45 0.669
rs3817334 MTCH2 11 T C 1.05 0.88-1.25 0.626
rs29942 KCTD15 19 C T 1.01 0.83-1.23 0.949
rs543874 SEC16B 1 G A 1.41 1.15-1.73 0.001
rs987237 TFAP2B 6 G A 1.27 1.02-1.59 0.032
rs7138803 FAIM2 12 A G 1.06 0.87-1.30 0.542
rs713586 RBJ 2 C T 1.19 1.00-1.42 0.048
rs2241423 MAP2K5 15 G A 1.34 1.12-1.59 0.001
rs2287019 QPCTL 19 C T 0.89 0.72-1.10 0.283
rs1514175 TNNI3K 1 A G 1.11 0.90-1.36 0.332
rs2112347 FLJ35779 5 T G 1.02 0.85-1.21 0.865
rs16912921 LRRN6C 9 A C 0.95 0.79-1.15 0.628
rs3810291 TMEM160 19 A G 0.93 0.77-1.12 0.456
rs1555543 PTBP2 1 C A 0.84 0.65-1.08 0.174
rs9579083 MTIF3 13 C G 1.08 0.85-1.37 0.519
rs4929949 RPL27A 11 C T 0.90 0.75-1.07 0.215
rs206936 NUDT3 6 G A 0.99 0.83-1.18 0.919
Scherag et al. 2010 (in children and adults of European ancestry)[6]
rs12145833 SDCCAG8 1 T G 0.96 0.71-1.31 0.799
rs13278851 TNKS/MSRA 8 A G 0.90 0.71-1.14 0.375
Bradfield et al. 2012 (in children of European ancestry) [5]
rs9568856 OLFM4 13 A G 1.08 0.89-1.30 0.438
rs9299 HOXB5 17 A G 1.07 0.90-1.27 0.449
Okada et al. 2012 (in East Asians) [8]
rs2206734 CDKAL1 6 G A 1.21 1.01-1.44 0.035
rs11142387 KLF9 9 C A 0.90 0.75-1.08 0.268
Wen et al. 2012 (in East Asians) [7]
rs261966 PCSK1 5 G A 1.03 0.87-1.22 0.764
rs12597579 GP2 16 C T 1.02 0.84-1.24 0.871
  1. SNP alleles which are associated with obesity risk in Chinese children are highlighted in bold. Chr. Chromosome