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Fig. 6 | BMC Medical Genetics

Fig. 6

From: A substitution mutation in cardiac ubiquitin ligase, FBXO32, is associated with an autosomal recessive form of dilated cardiomyopathy

Fig. 6

a Hematoxylin and eosin (H&E) and (b) trichrome staining of a left ventricular myocardial biopsy from the explanted heart of the proband showing hypertrophied myocytes, often with bizarrely shaped hyperchromatic nuclei and waving of the myocytes. c H&E and (d) trichrome staining from the control myocardium showing no cardiomyopathic changes, disarray, or fibrosis. e and (f) Immunohistochemical analysis of FBXO32 showing cytoplasmic staining with reduced protein expression in a section from the left ventricle of the proband (e) in comparison to a control myocardial specimen (f)

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BMC Medical Genetics

ISSN: 1471-2350

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