Table 1 Description of publicly available studies used in the meta-analysis
From: Integrative meta-analysis identifies microRNA-regulated networks in infantile hemangioma
Reference ID | Sample size | Gene expression analysis and validation analysis platforms |
|---|---|---|
[31] | 6 hemangiomas and 7 normal term placental tissues | U95Av2 GeneChip oligonucleotide microarrays (Affymetrix) |
[32] | 7 hemangiomas (3 proliferating, 4 involuting) and 3 normal term placental tissues | Human Genome U133 Plus 2.0 (Affymetrix) |
[33] | 4 pairs of early proliferative stage and spontaneously early involution stage of the same hemangiomas, 11 hemangiomas (6 proliferative and 5 involuting), 5 controls (normal skin) Serum from 69 patients with hemangioma (46 proliferative and 23 involuting), 20 patients with venous malformations and 31 negative controls (children with cheilopalatognathus) | Illumina Human-6 bead chip, QRT-PCR |
[34] GSE43742 | HEMECs, HDMVECs, 16 infantile hemangioma, 4 normal controls (neonatal foreskin) | Illumina HumanHT-12Â V4.0 expression beadchip Immunohistochemistry |
[35] | hemSCs, bm-MPCs, HDMECs, cbEPCs and abEPCs | RQ-PCR, Functional assays, Immunofluorescence |
[36] | HemSCs, HemECs, HDMECs and MSCs | RQ-PCR, Immunofluorescence |
[37] | 48 hemangiomas, 9 vascular malformations and vascular tumor specimens, 11 neonatal foreskin controls and HemECs from proliferating hemangioma | GeneFilter GF211 (Invitrogen) |