Placental DNA methylation at term reflects maternal serum levels of INHA and FN1, but not PAPPA, early in pregnancy

Table 3 Univariate linear analysis results (Protein Levels vs. Clinical parameters) in controls. Reported in correlation coefficient (r) values

Protein	N=	Fetal Sex	GA at Delivery	GA at Blood Draw^a	Birth Weight (SD)	Fetal Weight: Placental Weight	Placental Length:Breadth	Maternal BMI (Number of samples BMI was available)
INHA	36	0.20	0.00	NA	0.12	0.44*	0.30	0.34 (N = 18)
PAPPA	34	0.11	0.20	NA	0.26	0.08	0.00	0.05 (N = 21)
FN1	76	0.05	0.10	0.16	0.11	0.13	0.063	0.25* (N = 75, all samples)
FN1	76	0.05	0.10	0.16	0.11	0.13	0.063	0.10 (N = 37, control only

GA gestational age
*p < 0.05
^aOnly measured for FN1 as INHA and PAPPA levels were obtained from maternal serum screening program and already corrected for gestational age at blood draw

ISSN: 1471-2350