MTTP-297H polymorphism reduced serum cholesterol but increased risk of non-alcoholic fatty liver disease-a cross-sectional study

Table 4 Risk impact and interaction of the MTTP genotypes on serum LDL-C

Independent variables	Parameter estimates (B)	95 % Confidence interval		P
Independent variables	Parameter estimates (B)	Lower vs Upper bound		P
Age	0.430	0.150	0.710	0.003*
Sex (male vs female)	−7.279	−43.699	29.141	0.695
BMI	1.448	0.636	2.261	<0.0001*
HOMA-IR	−1.189	−3.543	1.166	0.322
Adipo-IR	1.414	−0.168	2.996	0.080
E98D (CC vs GG+GC)	−32.004	−96.849	32.840	0.333
I128T (CC vs TT+TC)	12.878	−7.070	32.827	0.205
N166S (GG vs AA+AG)	35.276	−27.455	98.007	0.270
Q297H (CC vs GG+GC)	−10.802	−17.822	−3.782	0.003*

Multiple linear regression analysis was applied using serum LDL-C as dependent variable adjusted by age, sex, BMI, HOMA-IR, Adipo-IR and MTTP genotypes based on significance in univariate analysis and regression models. (*P < 0.05 indicates significant)

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