Genotype | BMI (kg/m2) | P | TG (mg/dl) | P | HOMA-IR | P | Adipo-IR | P |
---|---|---|---|---|---|---|---|---|
(promoter) G-493T | Â | Â | ||||||
 GG+GT (n = 1155) | 24.5 ± 3.3 | 0.527 | 138.3 ± 123.9 | 0.039* | 1.09 ± 2.29 | 0.572 | 2.46 ± 3.84 | 0.014* |
 TT (n = 29) | 24.7 ± 2.5 |  | 117.1 ± 49.7 |  | 0.83 ± 0.72 |  | 1.61 ± 1.32 |  |
Glu98Asp (E98D) | Â | Â | ||||||
 GG+GC (n = 1127) | 24.5 ± 3.3 | 0.050* | 137.0 ± 120.9 | 0.001* | 1.09 ± 2.31 | 0.044* | 2.48 ± 3.87 | 0.436 |
 CC (n = 25) | 22.6 ± 2.3 |  | 101.3 ± 43.2 |  | 0.61 ± 1.02 |  | 1.78 ± 2.98 |  |
Ile128Thr (I128T) | Â | Â | ||||||
 TT+TC (n = 1148) | 24.5 ± 3.3 | 0.640 | 138.1 ± 123.6 | 0.040* | 1.08 ± 2.29 | 0.140 | 2.46 ± 3.86 | 0.017* |
 CC (n = 26) | 24.8 ± 2.6 |  | 114.9 ± 51.9 |  | 0.833 ± 0.75 |  | 1.57 ± 1.38 |  |
Asn166Ser (N166S) | Â | Â | ||||||
 AA+AG (n = 1145) | 24.5 ± 3.3 | 0.006* | 138.6 ± 123.9 | 0.001* | 1.05 ± 1.92 | 0.301 | 2.43 ± 2.75 | 0.442 |
 GG (n = 24) | 22.7 ± 2.3 |  | 102.8 ± 44.3 |  | 0.62 ± 1.04 |  | 1.77 ± 2.98 |  |
Gln297His (Q297H) | ||||||||
 GG+GC (n = 984) | 24.5 ± 3.4 | 0.913 | 136.9 ± 124.1 | 0.656 | 1.09 ± 2.43 | 0.451 | 0.57 ± 0.23 | 0.337 |
 CC (n = 193) | 24.5 ± 2.9 |  | 141.2 ± 116.2 |  | 0.92 ± 0.98 |  | 0.58 ± 0.25 |  |