Fig. 5
From: Relationships between putative G-quadruplex-forming sequences, RecQ helicases, and transcription
Self-organizing map analysis of PQS motifs in genes differentially-expressed in BS and WS. Multidimensional self-organizing map clustering of all human genome PQS within 2 kbp of TSS, based on total sequence length, loop lengths, number of G-stacks, and nucleotide base fractions. a PQS parameters for node centroids. b Counts of PQS binned by distance in multidimensional space to closest node. c Distance between nodes. d PQS node bias in genes differentially expressed in BS and WS. Bias represents number of unique PQS per node, normalized to dataset gene number, compared to the same calculation for all genes genome-wide. Green and red nodes represent positive (excess) or negative (scarcity) bias values that are outside of the 95 % CI for randomly-generated gene datasets of the same size. Green = excess. Red = scarcity. Gray = no statistically-significant difference