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Table 4 Significant gene x environment interactions with VEGF plasma levels

From: Angiogenesis related genes NOS3, CD14, MMP3 and IL4R are associated to VEGF gene expression and circulating levels in healthy adults

Interaction

Gene

β a(pg/ml)

t-values

P

rs1800779 × HDL-C

NOS3

0.12

2.78

0.005

rs1800779 × Triglycerides

NOS3

−0.04

−1.98

0.043

rs1800779 × Obesity

NOS3

−0.11

−2.36

0.018

rs6921438 × Hypertention

MGC45491 and MRPL14(near VEGF)

−0.18

−2.20

0.028

  1. a β, effect size