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Table 3 Epistatic interactions for VEGF plasma levels

From: Angiogenesis related genes NOS3, CD14, MMP3 and IL4R are associated to VEGF gene expression and circulating levels in healthy adults

SNP × SNP

Genes

β a(pg/ml)

t-values

P

rs1800779 × rs2569190

NOS3 × CD14

−0.07

−2.04

0.042

rs1800779 × rs3918226

NOS3 × NOS3

+0.17

2.29

0.022

rs1801275 × rs6921438

IL4R × VEGF

+0.08

2.043

0.042

rs1801275 × rs3025058

IL4R × MMP3

−0.10

−2.58

0.010

rs2569190 × rs3025058

CD14 × MMP3

+0.07

2.36

0.019

  1. a β, effect size
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BMC Medical Genetics

ISSN: 1471-2350

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