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Table 1 Patterns of inheritance, genes and number of alterations selected for the panel

From: Screening of genetic alterations related to non-syndromic hearing loss using MassARRAY iPLEX® technology

Inheritance Gene Locus No. of selected alterations OMIM Transcripts IDs
Autosomal recessive GJB2 DFNB1 22 121011 NM_004004
  SLC26A4 DFNB4 14 605646 NM_000441
  MYO15A DFNB3 5 602666 NM_016239
  OTOF DFNB9 16 603681 NM_194248
  CDH23 DFNB12 11 605516 NM_022124
  TMC1 DFNB7/11 4 606706 NM_138691
  TMPRSS3 DFNB8/10 5 605511 NM_024022
  TRIOBP DFNB28 1 609761 NM_001039141
  TMIE DFNB6 2 607237 NM_147196
  DFNB59 DFNB59 1 610219 NM_001042702
Autosomal dominant GJB2 DFNA3 1 121011 NM_004004
  WFS1 DFNA6/14 1 606201 NM_006005.3
  KCNQ4 DFNA2 1 603537 NM_004700
  COCH DFNA9 1 603196 NM_004086
  TECTA DFNA8/12 4 602574 NM_005422
  MIR-96 DFNA50 2 613074 NR_029512
Mitochondrial MT-RNR1 12S rRNA 2 561000 -
  MT-TS1 tRNASer(UCN) 1 590080 -