Table 5 Haplotype analysis of LOXL1 SNPs in XFG cases and controls participants in a Spanish population
From: LOXL1 gene variants and their association with pseudoexfoliation glaucoma (XFG) in Spanish patients
SNPs alleles | Haplotype frequency | Association test between XFG and Controls | |||||
|---|---|---|---|---|---|---|---|
rs16958477 | rs1048661 | rs3825942 | rs2165241 | XFG n = 105 | Control n = 200 | p value | OR (95% CI) |
C | G | G | T | 0.52 | 0.33 | 4.5×10-6 | 2.21 (1.36–3.59) |
A | T | G | C | 0.11 | 0.28 | 7.1×10-7 | 0.30 (0.15–0.60) |
A | G | G | T | 0.28 | 0.14 | 8.8×10-6 | 2.53 (1.41–4.55) |
A | G | A | C | 0.005 | 0.15 | 9.6×10-9 | 0.03 (0.00–0.43) |
C | T | G | C | 0.04 | 0.08 | 0.08 | 0.98 (0.41–2.35) |
A | G | G | C | 0.02 | 0.01 | 0.52 | 1.51 (0.25- 8.96) |