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Table 1 Characteristics of the study subjects

From: Polymorphism in microRNA-binding site in HNF1B influences the susceptibility of type 2 diabetes mellitus: a population based case–control study

 

T2DM

Control

P -value

 

n = 353

n = 448

 

Age (years)

54.4 ± 6.5

53.7 ± 5.1

0.12

BMI (kg/m2)

25.0 ± 3.6

23.1 ± 2.6

<0.0001

Glucose (mg/dl)*

155.0 ± 43.2

91.8 ± 4.9

<0.0001

HbA1c (%)

7.7 ± 1.57

5.4 ± 0.34

<0.0001

SBP (mmHg)

126.3 ± 15.6

120.5 ± 16.2

<0.0001

DBP (mmHg)

79.9 ± 11.0

76.8 ± 12.0

0.0002

Total-cholesterol (mg/dl)

212.5 ± 34.7

210.2 ± 31.7

0.33

LDL-cholesterol (mg/dl)

130.8 ± 29.9

129.5 ± 29.9

0.55

HDL-cholesterol (mg/dl)

54.0 ± 15.9

58.4 ± 16.4

0.0001

Triglyceride (mg/dl)*

161.8 ± 145.0

136.3 ± 112.8

0.0001

Obesity/Overweight (BMI ≥ 25) (%)

45.0

23.2

<0.0001

Current smoker (%)

43.7

41.8

0.61

  1. *Statistical test for glucose and triglyceride levels were caluculated on log-transformed values
  2. P-values between T2DM and control groups were caluculated by t-test or χ2 -test
  3. Data are expressed as mean ± SD or percentage