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Table 4 Genotype and allele frequencies of MDM2 SNP55 and SNP309 in cancer-free endometria and endometrial cancer samples

From: SNP55, a new functional polymorphism of MDM2-P2 promoter, contributes to allele-specific expression of MDM2 in endometrial cancers

 

Genotype

 

Alleles

 

SNP55 rs2870820

C/C

C/T

T/T

p-value

C

T

p-value

Cancer-free endometrial (n = 45)

17 (37.8 %)

24 (53.3 %)

4 (8.9 %)

 

58 (64.4 %)

32 (35.6 %)

 

Endometrial cancer (EMCA) (n =45)

17 (37.8 %)

22 (48.9 %)

6 (13.3 %)

0.87

56 (62.2 %)

34 (37.8 %)

0.88

SNP309 rs2279744

T/T

T/G

G/G

p-value

T

G

p-value

Cancer-free endometrial (n = 45)

12 (26.7 %)

24 (53.3 %)

9 (20.0 %)

 

48 (53.3 %)

42 (46.7 %)

 

Endometrial cancer (EMCA) (n =45)

14 (31.1 %)

21 (46.7 %)

10 (22.2 %)

0.85

49 (54.4 %)

41 (45.5 %)

1.00

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BMC Medical Genetics

ISSN: 1471-2350

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