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Fig. 2 | BMC Medical Genetics

Fig. 2

From: The importance of distinguishing between the odds ratio and the incidence rate ratio in GWAS

Fig. 2

The density of the three outcomes. The densities of the three types of outcome; death and two different diseases. The black solid line in subfigure A is the density function of a Gompertz distribution with density mode at age 85 and a shape parameter of 0.0004, i.e. the overall baseline. This is the likelihood of dying given an individual’s age. The black solid line in subfigures for Disease 1 and Disease 2 is the density function of a Gompertz distribution with density mode at age 25 and a shape parameter of 0.95 and mode at age 55 and shape parameter 0.1 respectively. This is the likelihood of getting diseased given an individual’s age. The coloured lines correspond to the likelihood of dying or developing the disease for different genotypes and different associations between the SNP and death

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