Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males: a case–control study

Table 2 Summary of eight SNPs used in analysis

SNP	Position^a	Gene name and function	Minor allele^b	Populations and reference	MAF^c CEU CHB
rs12129861	1q21.1	PDZK1, 5’Intergenic	A	European (17, 19, 20)	0.460 0.170
rs780094	2p23.3	GCKR, Intron16	A	European (17, 19, 20)	0.394 0.566
rs734553	4p10.1	SLC2A9, Intron7	C	European (17, 19, 20)	0.261 0.004
rs742132	6p22.2	LRRC16A, Intron34	C	European (17, 20)	0.301 0.244
rs742132	6p22.2	LRRC16A, Intron34	C	Japanese (21)	0.301 0.244
rs1183201	6p22.2	SLC17A1, Intron 3	A	European (17,20)	--- ---
rs12356193	10q21.2	SLC16A9, Intron 5	G	European (17, 19, 20)	0.186 0.141
rs17300741	11q13.1	SLC22A11, Intron4	G	European (17, 19, 20)	0.531 0.073
rs505802	11q13.1	SLC22A12, 5’Intergenic	A	European (17, 19, 20)	0.726 0.256

^aon human genome build 18
^bin NCBI
^ccollected from HapMap Data Phase III/Rel#3. CEU: Utah residents with Northern and Western European ancestry from the CEPH collection, CHB: Han Chinese in Beijing, China

ISSN: 1471-2350