TY - JOUR AU - Bugiani, M. AU - Boor, I. AU - Powers, J. M. AU - Scheper, G. C. AU - Knaap, M. S. PY - 2010 DA - 2010// TI - Leukoencephalopathy with vanishing white matter: a review JO - J Neuropathol Exp Neurol VL - 69 UR - https://doi.org/10.1097/NEN.0b013e3181f2eafa DO - 10.1097/NEN.0b013e3181f2eafa ID - Bugiani2010 ER - TY - JOUR AU - Liu, R. AU - Lei, H. D. AU - Wang, X. AU - Wortham, N. C. AU - Tang, H. AU - Berkel, C. G. PY - 2011 DA - 2011// TI - Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes JO - Hum Mutat VL - 32 UR - https://doi.org/10.1002/humu.21535 DO - 10.1002/humu.21535 ID - Liu2011 ER - TY - JOUR AU - Pavitt, G. D. AU - Proud, C. G. PY - 2009 DA - 2009// TI - Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease JO - Biochem Soc Trans VL - 37 UR - https://doi.org/10.1042/BST0371298 DO - 10.1042/BST0371298 ID - Pavitt2009 ER - TY - JOUR AU - Bugiani, M. AU - Boor, I. AU - Kollenburg, B. AU - Postma, N. AU - Polder, E. AU - Berkel, C. PY - 2011 DA - 2011// TI - Defective glial maturation in vanishing white matter disease JO - J Neuropathol Exp Neurol VL - 70 UR - https://doi.org/10.1097/NEN.0b013e318203ae74 DO - 10.1097/NEN.0b013e318203ae74 ID - Bugiani2011 ER - TY - JOUR AU - Cabilly, Y. AU - Barbi, M. AU - Geva, M. AU - Marom, L. AU - Chetrit, D. AU - Ehrlich, M. PY - 2012 DA - 2012// TI - Poor cerebral inflammatory response in eIF2B knock-in mice: implications for the aetiology of vanishing white matter disease JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0046715 DO - 10.1371/journal.pone.0046715 ID - Cabilly2012 ER - TY - JOUR AU - Geva, M. AU - Cabilly, Y. AU - Assaf, Y. AU - Mindroul, N. AU - Marom, L. AU - Raini, G. PY - 2010 DA - 2010// TI - A mouse model for eukaryotic translation initiation factor 2B-leucodystrophy reveals abnormal development of brain white matter JO - Brain VL - 133 UR - https://doi.org/10.1093/brain/awq180 DO - 10.1093/brain/awq180 ID - Geva2010 ER - TY - JOUR AU - Knaap, M. S. AU - Leegwater, P. A. AU - Konst, A. A. AU - Visser, A. AU - Naidu, S. AU - Oudejans, C. B. PY - 2002 DA - 2002// TI - Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter JO - Ann Neurol VL - 51 UR - https://doi.org/10.1002/ana.10112 DO - 10.1002/ana.10112 ID - Knaap2002 ER - TY - JOUR AU - Wortham, N. C. AU - Martinez, M. AU - Gordiyenko, Y. AU - Robinson, C. V. AU - Proud, C. G. PY - 2014 DA - 2014// TI - Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation JO - FASEB J VL - 28 UR - https://doi.org/10.1096/fj.13-243329 DO - 10.1096/fj.13-243329 ID - Wortham2014 ER - TY - JOUR AU - Hinnebusch, A. G. PY - 2011 DA - 2011// TI - Molecular mechanism of scanning and start codon selection in eukaryotes JO - Microbiol Mol Biol Rev VL - 75 UR - https://doi.org/10.1128/MMBR.00008-11 DO - 10.1128/MMBR.00008-11 ID - Hinnebusch2011 ER - TY - JOUR AU - Gomez, E. AU - Mohammad, S. S. AU - Pavitt, G. D. PY - 2002 DA - 2002// TI - Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation JO - EMBO J VL - 21 UR - https://doi.org/10.1093/emboj/cdf515 DO - 10.1093/emboj/cdf515 ID - Gomez2002 ER - TY - JOUR AU - Koonin, E. V. PY - 1995 DA - 1995// TI - Multidomain organization of eukaryotic guanine nucleotide exchange translation initiation factor eIF-2B subunits revealed by analysis of conserved sequence motifs JO - Protein Sci VL - 4 UR - https://doi.org/10.1002/pro.5560040819 DO - 10.1002/pro.5560040819 ID - Koonin1995 ER - TY - JOUR AU - Pavitt, G. D. AU - Ramaiah, K. V. AU - Kimball, S. R. AU - Hinnebusch, A. G. PY - 1998 DA - 1998// TI - eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange JO - Genes Dev VL - 12 UR - https://doi.org/10.1101/gad.12.4.514 DO - 10.1101/gad.12.4.514 ID - Pavitt1998 ER - TY - JOUR AU - Wang, X. AU - Wortham, N. C. AU - Liu, R. AU - Proud, C. G. PY - 2012 DA - 2012// TI - Identification of residues that underpin interactions within the eukaryotic initiation factor (eIF2) 2B complex JO - J Biol Chem VL - 287 UR - https://doi.org/10.1074/jbc.M111.331553 DO - 10.1074/jbc.M111.331553 ID - Wang2012 ER - TY - JOUR AU - Yang, W. AU - Hinnebusch, A. G. PY - 1996 DA - 1996// TI - Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2 JO - Mol Cell Biol VL - 16 UR - https://doi.org/10.1128/MCB.16.11.6603 DO - 10.1128/MCB.16.11.6603 ID - Yang1996 ER - TY - JOUR AU - Elsby, R. AU - Heiber, J. F. AU - Reid, P. AU - Kimball, S. R. AU - Pavitt, G. D. AU - Barber, G. N. PY - 2011 DA - 2011// TI - The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus JO - J Virol VL - 85 UR - https://doi.org/10.1128/JVI.05146-11 DO - 10.1128/JVI.05146-11 ID - Elsby2011 ER - TY - JOUR AU - Fabian, J. R. AU - Kimball, S. R. AU - Heinzinger, N. K. AU - Jefferson, L. S. PY - 1997 DA - 1997// TI - Subunit assembly and guanine nucleotide exchange activity of eukaryotic initiation factor-2B expressed in Sf9 cells JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.19.12359 DO - 10.1074/jbc.272.19.12359 ID - Fabian1997 ER - TY - JOUR AU - Wek, R. C. AU - Jiang, H. Y. AU - Anthony, T. G. PY - 2006 DA - 2006// TI - Coping with stress: eIF2 kinases and translational control JO - Biochem Soc Trans VL - 34 UR - https://doi.org/10.1042/BST0340007 DO - 10.1042/BST0340007 ID - Wek2006 ER - TY - JOUR AU - Kilberg, M. S. AU - Shan, J. AU - Su, N. PY - 2009 DA - 2009// TI - ATF4-dependent transcription mediates signaling of amino acid limitation JO - Trends Endocrinol Metab VL - 20 UR - https://doi.org/10.1016/j.tem.2009.05.008 DO - 10.1016/j.tem.2009.05.008 ID - Kilberg2009 ER - TY - JOUR AU - Voorn, J. P. AU - Kollenburg, B. AU - Bertrand, G. AU - Haren, K. AU - Scheper, G. C. AU - Powers, J. M. PY - 2005 DA - 2005// TI - The unfolded protein response in vanishing white matter disease JO - J Neuropathol Exp Neurol VL - 64 UR - https://doi.org/10.1097/01.jnen.0000178446.41595.3a DO - 10.1097/01.jnen.0000178446.41595.3a ID - Voorn2005 ER - TY - JOUR AU - Kollenburg, B. AU - Dijk, J. AU - Garbern, J. AU - Thomas, A. A. AU - Scheper, G. C. AU - Powers, J. M. PY - 2006 DA - 2006// TI - Glia-specific activation of all pathways of the unfolded protein response in vanishing white matter disease JO - J Neuropathol Exp Neurol VL - 65 UR - https://doi.org/10.1097/01.jnen.0000228201.27539.50 DO - 10.1097/01.jnen.0000228201.27539.50 ID - Kollenburg2006 ER - TY - JOUR AU - Kantor, L. AU - Pinchasi, D. AU - Mintz, M. AU - Hathout, Y. AU - Vanderver, A. AU - Elroy-Stein, O. PY - 2008 DA - 2008// TI - A point mutation in translation initiation factor 2B leads to a continuous hyper stress state in oligodendroglial-derived cells JO - PLoS One VL - 3 UR - https://doi.org/10.1371/journal.pone.0003783 DO - 10.1371/journal.pone.0003783 ID - Kantor2008 ER - TY - JOUR AU - Li, W. AU - Wang, X. AU - Knaap, M. S. AU - Proud, C. G. PY - 2004 DA - 2004// TI - Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways JO - Mol Cell Biol VL - 24 UR - https://doi.org/10.1128/MCB.24.8.3295-3306.2004 DO - 10.1128/MCB.24.8.3295-3306.2004 ID - Li2004 ER - TY - JOUR AU - Fogli, A. AU - Schiffmann, R. AU - Hugendubler, L. AU - Combes, P. AU - Bertini, E. AU - Rodriguez, D. PY - 2004 DA - 2004// TI - Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients JO - Eur J Hum Genet VL - 12 UR - https://doi.org/10.1038/sj.ejhg.5201189 DO - 10.1038/sj.ejhg.5201189 ID - Fogli2004 ER - TY - JOUR AU - Horzinski, L. AU - Huyghe, A. AU - Cardoso, M. C. AU - Gonthier, C. AU - Ouchchane, L. AU - Schiffmann, R. PY - 2009 DA - 2009// TI - Eukaryotic initiation factor 2B (eIF2B) GEF activity as a diagnostic tool for EIF2B-related disorders JO - PLoS One VL - 4 UR - https://doi.org/10.1371/journal.pone.0008318 DO - 10.1371/journal.pone.0008318 ID - Horzinski2009 ER - TY - JOUR AU - Jennings, M. D. AU - Pavitt, G. D. PY - 2010 DA - 2010// TI - eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation JO - Nature VL - 465 UR - https://doi.org/10.1038/nature09003 DO - 10.1038/nature09003 ID - Jennings2010 ER - TY - JOUR AU - Jennings, M. D. AU - Zhou, Y. AU - Mohammad-Qureshi, S. S. AU - Bennett, D. AU - Pavitt, G. D. PY - 2013 DA - 2013// TI - eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation JO - Genes Dev VL - 27 UR - https://doi.org/10.1101/gad.231514.113 DO - 10.1101/gad.231514.113 ID - Jennings2013 ER - TY - JOUR AU - Ohlenbusch, A. AU - Henneke, M. AU - Brockmann, K. AU - Goerg, M. AU - Hanefeld, F. AU - Kohlschutter, A. PY - 2005 DA - 2005// TI - Identification of ten novel mutations in patients with eIF2B-related disorders JO - Hum Mutat VL - 25 UR - https://doi.org/10.1002/humu.9325 DO - 10.1002/humu.9325 ID - Ohlenbusch2005 ER - TY - JOUR AU - Hannig, E. M. AU - Williams, N. P. AU - Wek, R. C. AU - Hinnebusch, A. G. PY - 1990 DA - 1990// TI - The translational activator GCN3 functions downstream from GCN1 and GCN2 in the regulatory pathway that couples GCN4 expression to amino acid availability in Saccharomyces cerevisiae JO - Genetics VL - 126 ID - Hannig1990 ER - TY - JOUR AU - Klein, U. AU - Ramirez, M. T. AU - Kobilka, B. K. AU - Zastrow, M. PY - 1997 DA - 1997// TI - A novel interaction between adrenergic receptors and the alpha-subunit of eukaryotic initiation factor 2B JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.31.19099 DO - 10.1074/jbc.272.31.19099 ID - Klein1997 ER - TY - JOUR AU - Richardson, J. P. AU - Mohammad, S. S. AU - Pavitt, G. D. PY - 2004 DA - 2004// TI - Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity JO - Mol Cell Biol VL - 24 UR - https://doi.org/10.1128/MCB.24.6.2352-2363.2004 DO - 10.1128/MCB.24.6.2352-2363.2004 ID - Richardson2004 ER - TY - JOUR AU - Hiyama, T. B. AU - Ito, T. AU - Imataka, H. AU - Yokoyama, S. PY - 2009 DA - 2009// TI - Crystal structure of the alpha subunit of human translation initiation factor 2B JO - J Mol Biol VL - 392 UR - https://doi.org/10.1016/j.jmb.2009.07.054 DO - 10.1016/j.jmb.2009.07.054 ID - Hiyama2009 ER - TY - JOUR AU - Pettersen, E. F. AU - Goddard, T. D. AU - Huang, C. C. AU - Couch, G. S. AU - Greenblatt, D. M. AU - Meng, E. C. PY - 2004 DA - 2004// TI - UCSF Chimera–a visualization system for exploratory research and analysis JO - J Comput Chem VL - 25 UR - https://doi.org/10.1002/jcc.20084 DO - 10.1002/jcc.20084 ID - Pettersen2004 ER - TY - JOUR AU - Maletkovic, J. AU - Schiffmann, R. AU - Gorospe, J. R. AU - Gordon, E. S. AU - Mintz, M. AU - Hoffman, E. P. PY - 2008 DA - 2008// TI - Genetic and clinical heterogeneity in eIF2B-related disorder JO - J Child Neurol VL - 23 UR - https://doi.org/10.1177/0883073807308705 DO - 10.1177/0883073807308705 ID - Maletkovic2008 ER - TY - JOUR AU - Pronk, J. C. AU - Kollenburg, B. AU - Scheper, G. C. AU - Knaap, M. S. PY - 2006 DA - 2006// TI - Vanishing white matter disease: a review with focus on its genetics JO - Ment Retard Dev Disabil Res Rev VL - 12 UR - https://doi.org/10.1002/mrdd.20104 DO - 10.1002/mrdd.20104 ID - Pronk2006 ER -