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Table 1 TERT genotype and allele frequencies stratified by race. ARIC study (1987–1989)

From: Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study

  African-American MAF White MAF p
dbSNP ID N %   N %   
rs2736122        
GG 1,857 56.1 0.25 5,283 53.8 0.27 0.04
AG 1,246 37.7   3,835 39.1   
AA 205 6.2   698 7.1   
rs4246742        
TT 1,444 43.5 0.35 7,037 71.6 0.15 <0.01
AT 1,453 43.8   2,549 25.9   
AA 421 12.7   241 2.5   
rs6863494        
TT 2,950 90.3 0.05 9,823 100..0 0.00 <0.01
CT 305 9.3   2 0.0   
CC 13 0.4   0 0.0   
rs4975605        
CC 1,012 30.6 0.45 2,742 27.9 0.47 <0.01
AC 1,619 48.9   4,861 49.5   
AA 679 20.5   2,218 22.6   
rs2736100*        
CC 683 20.6 0.54 2,533 25.8 0.49 <0.01
CA 1,661 50.0   4,932 50.2   
AA 975 29.4   2,361 24.0   
rs2853668        
GG 841 25.3 0.50 5,432 55.3 0.26 <0.01
TG 1,647 49.6   3,707 37.7   
TT 831 25.1   688 7.0   
  1. dbSNP, The National Center for Biotechnology Information’s SNP database; SNP, single nucleotide polymorphism; ID, identification; N, number; MAF, minor allele frequency; p, p-value for difference in genotype frequencies between racial groups evaluated by Pearson’s chi-squared test; *A allele previously associated with shorter telomere length [21]