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Table 1 TERT genotype and allele frequencies stratified by race. ARIC study (1987–1989)

From: Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study

 

African-American

MAF

White

MAF

p

dbSNP ID

N %

 

N %

  

rs2736122

       

GG

1,857

56.1

0.25

5,283

53.8

0.27

0.04

AG

1,246

37.7

 

3,835

39.1

  

AA

205

6.2

 

698

7.1

  

rs4246742

       

TT

1,444

43.5

0.35

7,037

71.6

0.15

<0.01

AT

1,453

43.8

 

2,549

25.9

  

AA

421

12.7

 

241

2.5

  

rs6863494

       

TT

2,950

90.3

0.05

9,823

100..0

0.00

<0.01

CT

305

9.3

 

2

0.0

  

CC

13

0.4

 

0

0.0

  

rs4975605

       

CC

1,012

30.6

0.45

2,742

27.9

0.47

<0.01

AC

1,619

48.9

 

4,861

49.5

  

AA

679

20.5

 

2,218

22.6

  

rs2736100*

       

CC

683

20.6

0.54

2,533

25.8

0.49

<0.01

CA

1,661

50.0

 

4,932

50.2

  

AA

975

29.4

 

2,361

24.0

  

rs2853668

       

GG

841

25.3

0.50

5,432

55.3

0.26

<0.01

TG

1,647

49.6

 

3,707

37.7

  

TT

831

25.1

 

688

7.0

  
  1. dbSNP, The National Center for Biotechnology Information’s SNP database; SNP, single nucleotide polymorphism; ID, identification; N, number; MAF, minor allele frequency; p, p-value for difference in genotype frequencies between racial groups evaluated by Pearson’s chi-squared test; *A allele previously associated with shorter telomere length [21]