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Table 4 Results of Mann Whitney test and mixed effects linear model for ratio R

From: Determining the genome-wide kinship coefficient seems unhelpful in distinguishing consanguineous couples with a high versus low risk for adverse reproductive outcome

  

Mean / Median

Mann Whitney test

Mixed effects model

  

Case

Control

p-value

β

p-value

PLINK (all)

All couples

0.276 / 0.313

0.347 / 0.338

0.907

−0.028

0.625

 

1st cousinsa

0.290 / 0.320

0.410 / 0.404

0.980

  

King robust (all)

All couples

−0.615 / -0.595

−0.462 / -0.534

0.990

−0.152

0.992

 

1st cousinsa

−0.580 / -0.550

−0.520 / -0.510

0.950

  

PLINK (by population)

All couples

0.209 / 0.145

0.594 / 0.233

0.991

−0.157

0.965

 

1st cousinsa

0.080 / 0.130

0.200 / 0.180

0.950

  

King homo (by population)

All couples

−0.506 / -0.490

−0.341 / -0.428

0.996

−0.086

0.980

 

1st cousinsa

−0.490 / -0.474

−0.430 / -0.428

0.940

  

IBDelphi

All couples

0.278 / 0.192

0.479 / 0.252

0.854

−0.085

0.834

 

1st cousinsa

0.058 / 0.057

0.160 / 0.160

0.950

  
  1. a Based on pedigree