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Table 4 Cox proportional hazard regression illustrating the risk of cardiovascular mortality in the C/C allele versus the C/G or G/G allele of rs266729 SNP of adiponetin adjusted for well-known clinical risk factors influencing cardiovascular risk in an elderly population during 80 months of follow-up

From: Gender difference in adiponectin associated with cardiovascular mortality

Variables   Total population   Males    Females   
  Hazard ratio 95 % CI p-value Hazard ratio 95 % CI p-value Hazard ratio 95 % CI p-value
Age 1,13 1.05-1.22 0.002 1.18 1.06-1.30 0.001 1.16 0.99-1.34 0.06
Hypertension 1.34 0.71-2.51 0.36 1.42 0.68-2.95 0.35 1.50 0.36-6.22 0.58
IHD 1.15 0.63-2.10 0.64 0.77 0.36-1.64 0.50 1.92 0.63-5.79 0.25
BMI 0.98 0.92-1.05 0.60 0.92 0.83-1.02 0.11 1.08 0.98-1.19 0.14
CRP 1.0 0.94-1.06 0.90 0.99 0.94-1.04 0.61 0.89 0.65-1.20 0.44
b-glucose 1.12 0.96-1.32 0.16 1.10 0.90-1.34 0.34 1.17 0.85-1.61 0.34
HDL 0.68 0.33-1.40 0.29 1.19 0.40-3.48 0.76 0.78 0.23-2.64 0.68
eGFR<60mL/min 1.25 0.71-2.20 0.43 0.85 0.43-1.70 0.65 4.24 1.08–16.60 0.04
Hb<120g/L 1.18 0.57-2.45 0.65 0.87 0.30-2.58 0.80 2.14 0.70-6.57 0.18
EF<40 % 1.78 0.84-3.77 0.13 2.40 0.97-5.97 0.06 2.45 0.48-12.36 0.28
Rs266729 C/C vs. C/G or G/G 1.54 0.91-2.61 0.11 0.87 0.47-1.62 0.66 9.35 1.99-43.91 0.005
  1. Note: BMI: Body mass index; CRP; C-reactive protein; eGFR: Estimated glomerular filtration rate; EF: Ejection fraction; HDL; High density lipoprotein