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Open Peer Review

This article has Open Peer Review reports available.

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Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and women

  • Andrée-Anne Houde1, 2,
  • Cécilia Légaré1, 2,
  • Simon Biron3, 4,
  • Odette Lescelleur3, 4,
  • Laurent Biertho3, 4,
  • Simon Marceau3, 4,
  • André Tchernof3, 5, 6,
  • Marie-Claude Vohl5, 6, 7,
  • Marie-France Hivert8, 9, 10 and
  • Luigi Bouchard1, 2Email author
BMC Medical Genetics201516:29

Received: 12 January 2015

Accepted: 22 April 2015

Published: 1 May 2015

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
12 Jan 2015 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
Author responded Author comments
Reviewed Reviewer Report
Reviewed Reviewer Report
Reviewed Reviewer Report
Resubmission - Version 3
Submitted Manuscript version 3
Author responded Author comments
Resubmission - Version 4
Submitted Manuscript version 4
22 Apr 2015 Editorially accepted
1 May 2015 Article published 10.1186/s12881-015-0174-1

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Department of Biochemistry, Université de Sherbrooke
ECOGENE-21 and Clinical Research Center and Lipid Clinic, Chicoutimi Hospital
Quebec Heart and Lung Institute
Department of Surgery, Laval University
Axe Endocrinologie et Néphrologie, Centre de recherche du CHU de Québec
Department of Food Science and Nutrition, Laval University
Institute of Nutrition & Functional Foods, Université Laval
Department of Medicine, Division of Endocrinology, Université de Sherbrooke
Department of Population Medicine, Harvard Pilgrim Health Care Institute
General Medicine Division, Massachusetts General Hospital