TGFβ-1 and TGFBR2 polymorphisms, cooking oil fume exposure and risk of lung adenocarcinoma in Chinese nonsmoking females: a case control study

Table 4 TGF-β1 C-509T and TGFBR2 G-875A polymorphisms and lung adenocarcinoma risk, stratified by fuel smoke exposure

Polymorphism	Exposure to fuel smoke					Non exposure to fuel smoke					P _interaction
	Cases	Controls	OR _adg	95% CI	P	Cases	Controls	OR _adg	95% CI	P
TGF-β1 C-509T											0.685
CC	21	17	1.0			57	62	1.0
CT	43	47	0.706	0.325-1.533	0.378	95	115	0.886	0.564-1.394	0.601
TT	14	21	0.501	0.195-1.289	0.152	42	51	0.883	0.512-1.523	0.601
CT/TT	57	68	0.642	0.305-1.353	0.244	137	166	0.885	0.578-1.356	0.576
TGFBR2 G-875A											0.922
GG	61	57	1.0			121	145	1.0
GA	15	24	0.594	0.280-1.257	0.173	65	78	0.987	0.655-1.488	0.951
AA	2	4	0.465	0.082-2.648	0.388	8	5	1.901	0.606-5.963	0.271
GA/AA	17	28	0.574	0.282-1.167	0.125	73	83	1.043	0.700-1.553	0.837

ISSN: 1471-2350