TGFβ-1 and TGFBR2 polymorphisms, cooking oil fume exposure and risk of lung adenocarcinoma in Chinese nonsmoking females: a case control study

Table 3 TGF-β1 C-509T and TGFBR2 G-875A polymorphisms and lung adenocarcinoma risk, stratified by cooking oil fume exposure

Polymorphism	Exposure to cooking oil fume					Non exposure to cooking oil fume					P _interaction
	Cases	Controls	OR _adg	95% CI	P	Cases	Controls	OR _adg	95% CI	P
TGF-β1 C-509T											0.046
CC	31	20	1.0			47	59	1.0
CT	54	40	0.887	0.441-1.784	0.737	84	122	0.841	0.523-1.354	0.477
TT	13	23	0.362	0.149-0.878	0.025	43	49	1.065	0.606-1.870	0.827
CT/TT	67	63	0.693	0.358-1.342	0.277	127	171	0.906	0.578-1.420	0.666
TGFBR2 G-875A											0.005
GG	59	60	1.0			123	142	1.0
GA	34	23	1.451	0.761-2.766	0.258	46	79	0.674	0.435-1.047	0.079
AA	5	0				5	9	0.629	0.205-1.929	0.417
GA/AA	39	23	1.664	0.883-3.136	0.115	51	88	0.670	0.439-1.022	0.063

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