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Table 2 TGFB1 C-509T and TGFBR2 G-875A polymorphisms and lung adenocarcinoma risk

From: TGFβ-1 and TGFBR2 polymorphisms, cooking oil fume exposure and risk of lung adenocarcinoma in Chinese nonsmoking females: a case control study

Polymorphism

Cases

Controls

OR adg

95% CI

P

TGF-β1 C-509T

     

CC

78(28.7)

79(25.2)

1.0

  

CT

138(50.7)

162(51.8)

0.847

0.574-1.249

0.402

TT

56(20.6)

72(23.0)

0.768

0.480-1.228

0.270

CT/TT

194(71.3)

234(74.8)

0.822

0.569-1.188

0.298

C

294(54.0)

320(51.1)

1.0

  

T

250(46.0)

306(48.9)

0.878

0.697-1.106

0.270

TGFBR2 G-875A

     

GG

182(66.9)

202(64.5)

1.0

  

GA

80(29.4)

102(32.6)

0.865

0.605-1.237

0.427

AA

10(3.7)

9(2.9)

1.223

0.486-3.078

0.669

GA/AA

90(33.1)

111(35.5)

0.895

0.634-1.263

0.528

G

444(81.6)

506(80.8)

1.0

  

A

100(18.4)

120(19.2)

0.946

0.704-1.271

0.711

Combined analysis

     

0 Variant locus

54(19.9)

42(13.4)

1.0

  

1Variant locus

152(55.9)

197(62.9)

0.591

0.374-0.935

0.025

2 Variant locus

66(24.3)

74(23.6)

0.675

0.399-1.141

0.142

  1. Abbreviation:OR adg age-adjusted odds ratio, CI confidence interval.