Table 2 Distributions of toll-like receptor genotypes in the three groups

rs5743618

GG

2(0.5)

2(0.9)

1(0.9)

0.613

1.883

0.264-13.461

0.979

1.032

0.093-11.511

0.499

1.944

0.175-21.64

TG

70(16.6)

23(10.2)

10(9.2)

0.028

0.573

0.347-0.946

0.763

0.887

0.407-1.936

0.054

0.508

0.252-1.022

TT

350(82.9)

200(88.9)

98(89.9)

0.043

1.646

1.011-2.678

0.778

1.114

0.526-2.356

0.074

1.833

0.935-3.592

rs3804099

CC

51(12.1)

25(11.1)

9(8.3)

0.714

0.909

0.547-1.512

0.419

0.720

0.324-1.600

0.260

0.655

0.312-1.375

TC

180(42.6)

95(42.2)

36(33.0)

0.916

0.982

0.708-1.363

0.107

0.675

0.418-1.089

0.068

0.663

0.426-1.033

TT

191(45.3)

105(46.7)

64(58.7)

0.732

1.058

0.765-1.464

0.039

1.625

1.023-2.581

0.012

1.720

1.123-2.636

rs5743708

GA

4(0.9)

9(4.0)

6(5.5)

0.008

4.354

1.326-14.301

0.534

1.398

0.485-4.033

0.002

6.087

1.687-21.968^a

GG

418(99.1)

216(96.0)

103(94.5)

0.008

0.229

0.051-0.836

0.534

0.715

0.221-2.513

0.002

0.164

0.046-0.593^a

rs3804100

CC

42(10.0)

45(20.0)

21(19.2)

<0.001

2.262

1.433-3.570^a

0.875

0.955

0.536-1.700

0.007

2.159

1.218-3.829

TC

168(39.8)

90(40.0)

44(40.4)

0.963

1.008

0.724-1.402

0.949

1.015

0.637-1.619

0.916

1.023

0.666-1.572

TT

212(50.2)

90(40.0)

44(40.4)

0.013

0.660

0.476-0.917

0.949

0.985

0.618-1.570

0.066

0.671

0.437-1.028

rs1898830

AA

142(33.6)

68(30.2)

33(30.3)

0.375

0.854

0.602-1.211

0.992

1.003

0.609-1.649

0.504

0.856

0.543-1.351

AG

196(46.4)

113(50.2)

54(49.5)

0.360

1.163

0.842-1.608

0.907

0.973

0.616-1.538

0.564

1.132

0.743-1.725

GG

84(20.0)

44(19.6)

22(20.2)

0.915

0.978

0.651-1.469

0.893

1.040

0.587-1.843

0.948

1.018

0.602-1.720

rs4986790

AA

346(82.0)

181(80.4)

77(70.6)

0.630

0.904

0.598-1.365

0.045

0.585

0.345-0.991

0.009

0.529

0.327-0.855

AG

75(17.8)

42(18.7)

31(28.4)

0.778

1.062

0.699-1.613

0.043

1.732

1.094-3.050

0.013

1.839

1.132-2.987

GG

1(0.2)

2(0.9)

1(0.9)

0.245

3.776

0.341-41.869

0.979

1.032

0.093-11.51

0.369

3.898

0.242-62.825

rs4986791

CC

342(81.0)

179(79.6)

74(67.9)

0.649

0.910

0.607-1.365

0.020

0.543

0.324-0.911

0.003

0.495

0.309-0.791

CT

76(18.0)

43(19.1)

32(29.4)

0.730

1.076

0.710-1.629

0.035

1.759

1.036-2.987

0.009

1.892

1.169-3.061

TT

4(1.0)

3(1.3)

3(2.7)

0.699

1.412

0.313-6.365

0.396

2.094

0.416-10.551

0.141

2.958

0.652-13.415

rs11536889

CC

34(8.1)

17(7.6)

10(9.2)

0.822

0.933

0.509-1.701

0.611

1.236

0.546-2.798

0.706

1.153

0.551-2.413

GC

167(39.5)

86(38.2)

40(36.7)

0.737

0.945

0.678-1.317

0.787

0.937

0.584-1.504

0.583

0.885

0.573-1.368

GG

221(52.4)

122(54.2)

59(54.1)

0.653

1.077

0.779-1.490

0.987

0.996

0.630-1.577

0.743

1.073

0.703-1.637

rs10759932

CC

42(10.0)

21(9.3)

5(4.5)

0.800

0.931

0.537-1.616

0.129

0.467

0.171-1.274

0.079

0.435

0.168-1.127

TC

168(39.8)

90(40.0)

49(45.0)

0.963

1.008

0.724-1.402

0.389

1.225

0.772-1.945

0.330

1.235

0.807-1.888

TT

212(50.2)

114(50.7)

55(50.5)

0.917

1.017

0.736-1.406

0.972

0.992

0.628-1.567

0.967

1.009

0.662-1.537

rs7873784

CC

29(6.9)

19(8.4)

7(6.4)

0.467

1.250

0.684-2.283

0.518

0.744

0.303-1.827

0.868

0.930

0.396-2.184

GC

135(32.0)

57(25.4)

18(16.5)

0.078

0.721

0.501-1.037

0.070

0.583

0.324-1.050

0.001

0.421

0.244-0.726^a

GG

258(61.1)

149(66.2)

84(77.1)

0.202

1.246

0.888-1.748

0.043

1.714

1.014-2.897

0.002

2.136

1.312-3.478^a

rs10759931

AA

143(33.9)

90(40.0)

44(40.4)

0.123

1.301

0.931-1.817

0.949

1.015

0.637-1.619

0.207

1.321

0.857-2.035

AG

215(50.9)

113(50.2)

54(49.5)

0.860

0.971

0.703-1.343

0.907

0.973

0.616-1.538

0.793

0.945

0.620-1.440

GG

64(15.2)

22(9.8)

11(10.1)

0.055

0.606

0.363-1.014

0.928

1.036

0.483-2.221

0.175

0.628

0.319-1.236

rs5743810

CT

12(2.8)

8(3.6)

5(4.6)

0.618

1.260

0.507-3.128

0.648

1.304

0.416-4.084

0.357

1.643

0.566-4.766

TT

410(97.2)

217(96.4)

104(95.4)

0.618

0.790

0.293-2.276

0.648

0.773

0.215-3.057

0.357

0.609

0.210-1.766

TLR8_129

CC

133(31.5)

81(36.0)

52(47.7)

0.248

1.222

0.869-1.719

0.040

1.622

1.020-2.580

0.002

1.982

1.292-3.042^a

CG

190(45.0)

96(42.7)

41(37.6)

0.565

0.909

0.656-1.259

0.379

0.810

0.507-1.295

0.164

0.736

0.478-1.134

GG

99(23.5)

48(21.3)

16(14.7)

0.539

0.885

0.599-1.307

0.147

0.634

0.342-1.178

0.047

0.561

0.315-0.999

rs5743836

CC

25(5.9)

13(5.8)

6(5.5)

0.940

0.974

0.488-1.943

0.919

0.950

0.351-2.571

0.868

0.925

0.370-2.314

TC

181(42.9)

125(55.5)

49(45.0)

0.002

1.664

1.201-2.306

0.069

0.653

0.412-1.035

0.698

1.087

0.712-1.661

TT

216(51.2)

87(38.7)

54(49.5)

0.002

0.601

0.433-0.836

0.059

1.557

0.982-2.471

0.760

0.936

0.614-1.427

rs1870884

CC

3(0.7)

1(0.4)

0(0)

1.000

0.624

0.064-6.029

-

TC

107(25.4)

56(24.9)

27(24.8)

0.896

0.976

0.672-1.417

0.981

0.994

0.585-1.687

0.900

0.969

0.596-1.578

TT

312(73.9)

168(74.7)

82(75.2)

0.839

1.039

0.717-1.506

0.912

1.030

0.607-1.748

0.783

1.071

0.658-1.741

TIRAP_975

CC

313(74.2)

153(68.0)

61(56.0)

0.096

0.740

0.519-1.055

0.032

0.598

0.374-0.957

<0.001

0.443

0.286-0.685^a

CT

97(23.0)

61(27.1)

40(36.7)

0.245

1.246

0.860-1.806

0.074

1.559

0.957-2.539

0.004

1.942

1.238-3.048

TT

12(2.8)

11(4.9)

8(7.3)

0.181

1.756

0.762-4.046

0.365

1.541

0.601-3.949

0.028

2.706

1.078-6.796