RNASET2 tag SNP but not CCR6 polymorphisms is associated with autoimmune thyroid diseases in the Chinese Han population

Table 6 Haplotype analysis of AITDs patients and controls

Haplotype	Controls (Frequency)	AITD	P	OR (95% CI)	GD (Frequency)	P	OR (95% CI)	HT (Frequency)	P	OR (95% CI)
Block 1
AT	952(53.3)	1010(49.4)	0.016	0.856	644(47.9)	0.003	0.806 (0.699-0.929)	366(52.2)	0.626	-
AT	952(53.3)	1010(49.4)	0.016	0.754-0.972	644(47.9)	0.003	0.806 (0.699-0.929)	366(52.2)	0.626	-
GC	663(37.2)	795(38.9)	0.265	-	536(39.9)	0.116	-	259(37.0)	0.955	-
GT	160(8.9)	223(11.0)	0.045	1.245	149(11.1)	0.048	1.267 (1.001-1.603)	74(10.6)	0.215	-
GT	160(8.9)	223(11.0)	0.045	1.005-1.541	149(11.1)	0.048	1.267 (1.001-1.603)	74(10.6)	0.215	-
Block 2
GG	1079(60.5)	1188(58.2)	0.136		774(57.7)	0.105	-	414(59.1)	0.519	-
AA	703(39.5)	854(41.8)	0.136		568(42.3)	0.105	-	286(40.9)	0.519	-

AITDs, autoimmune thyroid diseases; GD, Graves’ disease; HT, Hashimoto’s thyroiditis; OR, odds ratio; CI, confidence interval.

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