Figure 2
Mean HDLC levels in smoking status categories by rs4977574 genotype in MDC-CC. The G allele was only associated with lower levels of HDLC among never-smokers (β = −0.02 mmol/L, SE = 0.008 per G allele, P = 0.045). Higher risk categories of smoking were associated with lower HDLC for all genotypes. The magnitude of this association was largest among individuals with AA genotype (β = −0.05 mmol/L, SE = 0.01 per higher risk category, P = 1 × 10−7) compared with AG (β = −0.03 mmol/L, SE = 0.009 per higher risk category, P = 0.0004) and GG (β = −0.02 mmol/L, SE = 0.01 per higher risk category, P = 0.024) genotypes.