A study of genes encoding cytokines (IL6, IL10, TNF), cytokine receptors (IL6R, IL6ST), and glucocorticoid receptor (NR3C1) and susceptibility to bronchopulmonary dysplasia

Table 4 Results of epistasis analysis in the northern Finnish population

Chr 1	Gene 1	SNP 1	Chr 2	Gene 2	SNP 2	Pvalue of interaction*
1	IL10	rs3024493	5	IL6ST	rs10471960	0.0003
1	IL6R	rs1386821	7	IL6	rs2069832	0.0025
5	NR3CI	rs17209237	6	TNF	rs1800629	0.0049
1	IL10	rs3024493	5	NR3C1	rs17209237	0.0063

*None of the interactions were significant after correcting for multiple comparisons (P <0.0002 as threshold for significance). Only SNP x SNP interactions with P values <0.01 are shown.

ISSN: 1471-2350