Figure 4
From: Genome-wide linkage and exome analyses identify variants of HMCN1for splenic epidermoid cyst
Genomic context of HMCN1 domains and variants with their across-species conservation. (A) Domain structures of partial HMCN1 are illustrated. TSP1 denotes thrombospondin type 1 domain and cb-EGF denotes calcium-binding epidermal growth factor like domain. The repetitive Immunoglobulin like (Ig-like) domain is also presented. (B) The genomic context of HMCN1 variants and the corresponding amino acid substitutions with their physical position. (C) Across-species conservation of the variants' positions indicating a conserved pattern except for chicken and zebrafish.