BMC Medical Genetics

Table 2 Genes common in males and females that were validated by qPCR

From: Identification of genes with altered expression in male and female Schlager hypertensive mice

	Male			Female
Gene	FC qPCR	P value qPCR	FC (array)	FC qPCR	P value qPCR	FC (array)
Hdc	1154	<0.001	1.86	5.0	<0.001	1.10
Gabra3	97	<0.001	1.53	128	<0.001	1.56
Angptl7	53	<0.001	1.47	89	<0.001	1.68
Cyp4b1	12.2	<0.001	1.15	20.4	<0.001	1.39
Edn3	4.4	<0.001	1.14	3.8	<0.001	1.16
Dna2	1.7	0.001	1.12	1.4	0.02	1.08
Cndp2	1.4	0.01	1.12	1.9	0.03	1.08
Mcm6	−10	<0.001	−1.30	−8.7	<0.001	−1.30
Vwa1	−10	<0.001	−1.23	−3.0	<0.001	−1.14
Kcnk1	−3.3	<0.001	−1.15	−3.2	<0.001	−1.18
Serpinb8	−2.5	<0.001	−1.21	−2.7	<0.001	−1.22
Pld1	−2.0	0.001	−1.11	−1.4	0.02	−1.11
Pter	−1.7	0.001	−1.03	−1.5	<0.001	−1.03
Pak6	−1.7	<0.001	−1.10	−1.3	0.03	−1.11
Il10rb	−1.3	0.004	−1.07	−1.3	0.01	−1.06

Values represent mean fold changes (FC) between BPH/2J and BPN/3J samples relative to BPN/3J. Positive values indicate higher expression in BPH/2J samples while, negative values indicate lower expression in BPH/2J samples.

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