Figure 2
From: Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya
Association testing for effects independent of c.202G>A. a, -Log10 P-values and b, estimated allelic effect sizes from `controlled’ association tests (covariates: gender, c.202G>A genotype). The twelve polymorphisms exhibiting significant effects at P<0.001 are colored according to whether they exhibit positive ES (green) or negative ES (red). Gene graphic shows exons (blue) and introns (yellow) for genes annotated at UCSC Genome Browser (hg19); IKBKG=inhibitor of nuclear factor kappa-B kinase subunit gamma.