Table 4 Subgroup-analysis of the miR-146a rs2910164 polymorphisms and HCC risk
Subgroup | Comparisons | Test of association | Test of heterogeneity | ||||
|---|---|---|---|---|---|---|---|
OR | 95%CI | P value | Model | I2 | P value | ||
Population | Â | Â | Â | Â | Â | Â | Â |
Chinese | 8 | 1.174 | 1.099-1.253 | <0.001 | F | 38.5% | 0.123 |
Other | 2 | 0.939 | 0.752-1.172 | 0.577 | F | 0.0% | 0.875 |
Genotyping method | Â | Â | Â | Â | Â | Â | Â |
PCR-RFLP | 5 | 1.103 | 0.982-1.239 | 0.097 | F | 25.8% | 0.249 |
Other | 5 | 1.174 | 1.090-1.265 | <0.001 | F | 54.6% | 0.066 |
Sample size | Â | Â | Â | Â | Â | Â | Â |
<700 | 6 | 1.129 | 1.010-1.262 | 0.033 | F | 31.3% | 0.201 |
>700 | 4 | 1.164 | 1.079-1.256 | <0.001 | F | 60.0% | 0.057 |