BMC Medical Genetics

Table 5 Regression coefficients ( $\hat{β}$ ) showing the association between birth weight score and lipid and lipoprotein levels by APOE genotypes and sex after controlling for age, pubertal stage, socioeconomic status, gestational age, body mass index and cardiorespiratory fitness

From: Birth weight and blood lipid levels in Spanish adolescents: Influence of selected APOE, APOC3 and PPARgamma2 gene polymorphisms. The AVENA Study

	Males (n = 260)						Females (n = 242)
	ε2/ε3		ε3/ε3		ε3/ε4		ε2/ε3		ε3/ε3		ε3/ε4
	$\hat{β}$	P value	$\hat{β}$	P value	$\hat{β}$	P value	$\hat{β}$	P value	$\hat{β}$	P value	$\hat{β}$	P value
TC*	0.019	0.976	0.198	0.065	-0.401	0.042	0.787	0.353	0.157	0.197	-0.313	0.262
HDLc*	0.487	0.242	0.285	0.011	0.262	0.238	0.797	0.427	0.153	0.195	0.525	0.027
LDLc*	-0.109	0.787	0.121	0.260	-0.622	0.003	0.458	0.566	0.116	0.354	-0.302	0.264
TG*	-0.023	0.956	0.001	0.988	0.048	0.824	0.610	0.031	-0.153	0.171	-0.477	0.039
apoA*	0.424	0.326	0.236	0.022	0.328	0.125	0.698	0.314	0.150	0.900	-0.267	0.278
apoB*	-0.092	0.820	0.160	0.145	-0.554	0.008	0.428	0.540	-0.172	0.172	-0.076	0.780
Lp(a)*	-0.064	0.863	0.122	0.259	-0.625	0.002	-0.301	0.743	0.054	0.667	0.054	0.843
TC-HDLc	-0.019	0.663	0.127	0.227	-0.454	0.024	0.518	0.522	0.085	0.501	-0.060	0.816
TC/HDLc	-0.402	0.286	0.014	0.889	-0.406	0.028	0.106	0.900	-0.041	0.742	0.243	0.291
apoB/apoA	-0.333	0.387	-0.007	0.946	-0.518	0.011	0.142	0.850	0.047	0.699	0.130	0.588

TC indicates total cholesterol; HDLc, high density liprotein cholesterol; LDLc, low density lipoprotein cholesterol; TG, triglycerides; Apo, apolipoprotein; Lp(a), lipoprotein a.
*Analyses were performed on log transformed data.

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