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Table 4 Lipid and lipoprotein levels (mg/dl) and body mass index (kg/m2) according to the APOC3 genotypes and sex

From: Birth weight and blood lipid levels in Spanish adolescents: Influence of selected APOE, APOC3 and PPARgamma2 gene polymorphisms. The AVENA Study

 

Males (n = 260)

Females (n = 242)

Genotype

S1/S1

S1/S2

P value

S1/S1

S1/S2

P value

n (%)

214 (82.1)

46 (17.0)

 

198 (81.8)

44 (18.2)

 

TC*

156.2 ± 26.4

159.7 ± 27.0

NS

167.2 ± 25.2

181.9 ± 28.9

<0.001

HDLc*

51.0 ± 9.4

51.1 ± 11.4

NS

59.0 ± 11.4

60.0 ± 12.0

NS

LDLc*

91.1 ± 23.7

93.3 ± 25.2

NS

95.5 ± 22.4

106.3 ± 25.7

NS

TG*

70.5 ± 31.7

76.1 ± 31.3

NS

63.5 ± 26.1

70.6 ± 27.8

NS

apoA*

117.6 ± 17.2

114.1 ± 16.5

NS

127.0 ± 19.5

130.2 ± 18.1

NS

apoB*

66.6 ± 14.4

68.4 ± 14.0

NS

68.8 ± 13.1

74.9 ± 16.1

NS

Lp(a)*

31.2 ± 37.1

27.9 ± 32.4

NS

32.5 ± 39.4

31.8 ± 36.8

NS

TC-HDLc

105.2 ± 25.7

108.6 ± 27.0

NS

108.2 ± 23.9

121.8 ± 31.4

<0.01

TC/HDLc

3.2 ± 0.7

3.3 ± 0.8

NS

2.9 ± 0.6

3.2 ± 0.9

NS

apoB/apoA

0.6 ± 0.1

0.6 ± 0.2

NS

0.6 ± 0.1

0.6 ± 0.2

NS

BMI

22.1 ± 3.9

22.2 ± 3.8

NS

21.5 ± 3.4

22.6 ± 4.0

NS

  1. Values are expressed as mean ± standard deviation, otherwise stated.
  2. P value from ANOVA, adjusted for mass significance.
  3. TC indicates total cholesterol; HDLc, high density liprotein cholesterol; LDLc, low density lipoprotein cholesterol; TG, triglycerides; Apo, apolipoprotein; Lp(a), lipoprotein (a); NS, not significant
  4. *Analyses were performed on log transformed data, but non-transformed data are presented in the table.
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BMC Medical Genetics

ISSN: 1471-2350

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