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Table 2 Non-synonymous sequence variants within the oxygen-dependent degradation domain of the HIF1A gene with pre-eclamptic first pregnancies (N = 108) and women with normotensive pregnancies (N = 101)

From: Non-synonymous sequence variants within the oxygen-dependent degradation domain of the HIF1Agene are not associated with pre-eclampsia in the Finnish population

Variation Amino acid No. of alleles in cases No. of alleles in controls P-value* OR (95% CI)
rs11549465 (c.1744C>T)      
C allele Pro582 208 189 0.26 0.56 (0.23–1.38)
T allele Ser582 8 13   
rs11529467 (c.1762G>A)      
G allele Ala588 212 199 1.00 1.25 (0.28–5.66)
A allele Thr588 4 3   
  1. *Fisher's exact test