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Table 1 Frequencies of SREBP-2 polymorphisms in AVN and normal subjects

From: Significant association of SREBP-2genetic polymorphisms with avascular necrosis in the Korean population

Loci

Position

rs#

Genotype

MAF

Heterozygosity

HWE

          

Control

Case all

Alcohol

Idiopathic

Steroid

IVS1+8408 T>C

Intron1

rs2267439

 

TT

CT

CC

N

  

0.714

0.619

0.653

1

0.428

   

AVN

159

218

66

443

0.395

0.492

     
   

CTL

77

138

55

270

0.459

0.511

     

IVS3-342 G>T

Intron2

rs2269657

 

GG

GT

TT

N

  

0.637

0.71

0.469

1

1

   

AVN

241

149

32

422

0.263

0.353

     
   

CTL

146

107

16

269

0.258

0.398

     

IVS11+414 G>A

Intron11

rs1052717

 

GG

AG

AA

N

  

0.301

0.331

0.334

0.184

0.237

   

AVN

202

186

53

441

0.331

0.422

     
   

CTL

132

120

19

271

0.292

0.443

     

IVS12-1667 G>A

Intron11

rs2267443

 

GG

AG

AA

N

  

0.891

0.267

1

0.077

1

   

AVN

169

192

69

430

0.384

0.447

     
   

CTL

116

121

29

266

0.337

0.455