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Table 2 Additive genotype-by-diabetes interaction for obesity related quantitative traits in American Indian participants of the Strong Heart Family Study

From: Diabetes-specific genetic effects on obesity traits in American Indian populations: the Strong Heart Family Study

     Genetic standard deviation
Obesity traits Variance due to covariates* Residual kurtosis after covariates Genetic correlation (ρG) ± SE among diabetics and nondiabetics (P-value) Diabetic individuals Non-diabetic individuals P-value**
Weight 0.11 0.55 0.56 ± 0.16 (0.01) 15.56 18.83 0.26
BMI 0.09 0.75 0.45 ± 0.17 (0.0002) 6.26 5.56 0.50
% FAT 0.47 0.96 0.67 ± 0.18 (0.08) 5.58 7.46 0.16
WHR† 0.22 0.57 0.72 ± 0.15 (0.02) 5.77 5.51 0.77
  1. BMI, body mass index; WHR, waist-to-hip ratio; FAT, body fat; SE, standard error. * age, sex, center; ** P-values for the likelihood ratio comparing a model in which the genetic variances for obesity traits in diabetics and non-diabetics are equal to a model without constrains. †The trait was scaled by multiplying by 100.